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Canine Coagulation Factor VII is an important protein involved in blood clotting in dogs.
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Caractéristiques
| Breeds | Braque allemand à poil court, Catahoula Leopard Dog, Chien d'arrêt allemand à poil dur, Chien de chasse finlandais, Deerhound écossais, Foxhound anglais, Harrier, Husky d’Alaska, Japanese Spitz, Lévrier whippet, Redbone Coonhound, Schnauzer (Giant), Schnauzer (Miniature), Sealyham Terrier, Teckel, Welsh Springer Spaniel, Airedale Terrier, Alaskan Klee Kai, Irish Water Spaniel, American Foxhound, Basset Hound, Beagle, Papillon, Phalène |
|---|---|
| Gene | |
| Chromosome | 22 |
| Mutation | c.407G>A |
| Mode of Inheritance | Autosomique récessif |
| Organ | |
| Specimen | Écouvillon, EDTA sanguin, Héparine sanguine, Sperme, Tissu |
Informations générales
Canine Coagulation Factor VII is an important protein involved in blood clotting in dogs. Deficiency in Factor VII causes a bleeding disorder, which can lead to dangerously uncontrolled bleeding in the case of injury or surgery. The disorder occurs in a wide range of breeds, including the Airedale Terrier, Beagle, German Wirehaired Pointer and Scottish Deerhound. It is caused by a recessive mutation to the gene F7.
Caractéristiques cliniques
Under most circumstances, affected dogs appear healthy. However, they may bleed excessively after trauma or surgery, develop hematomas or bleeding in the body cavity, or experience persistent uterine or vaginal bleeding. Blood analysis can confirm a lack of Factor VII activity.
Additional Information
Références
Pubmed ID: 16961583
Year published: 2006
Omia ID: 361
Omia variant ID: 40