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The White Spotting coat colour pattern in horses can be caused by any in a wide array of related mutations.
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Caractéristiques
| Breeds | |
|---|---|
| Gene | |
| Chromosome | 3 |
| Mutation | c.2369delC |
| Mode of Inheritance | Autosomique dominante |
| Organ | |
| Specimen | Hair, Blood EDTA, Blood Heparin, Semen, Tissue |
| Also known as | W21 |
Informations générales
The White Spotting coat colour pattern in horses can be caused by any in a wide array of related mutations. The resulting pattern can vary anywhere between white markings on the face and legs, up to a completely white coat. Depending on both breed and pattern, variants of the White Spotting phenotype may be referred to as Splashed White, Dominant White, Tobiano or Sabino, among others.
The specific variant analysed in this test, known as Dominant White 21 (W21), is caused by an autosomal dominant mutation to the gene KIT. It has been observed in the Icelandic horse.
Caractéristiques cliniques
The colouration caused by the W21 mutation typically display a mostly white face accompanied by speckling and irregular patches of white distributed over the body.
Additional Information
Coat colour is an intricate trait that involves a combination of multiple different genes. Testing for a range of different loci will give the most complete prediction of a horse's coat colour genetics.
White Spotting can be caused by a wide range of mutations. A white-patterned horse that tests as unaffected for a particular mutation will almost certainly be affected by a different one.
Références
Pubmed ID: 26059442
Year published: 2015
Omia ID: 000209
Omia variant ID: 891