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H819

Coat colour in dogs is controlled by a wide range of different genes working together.

10 working days

Caractéristiques

Breeds

Gene

Organ

specimen

Swab, Blood EDTA, Blood Heparin, Semen, Tissue
Mode of Inheritance

Chromosome

Also known as

Year Published

Informations générales

Coat colour in dogs is controlled by a wide range of different genes working together. These genes are often referred to as ‘loci’. The Dominant Black, or K-Locus, corresponds to the gene ‘beta-defensin 103’ (CBD103), which plays a significant role in pigmentation. A dominant mutation to CBD103, designated as K^B, results in an all-black coat colour. The recessive, unaffected allele of the K-Locus is designated as k^y, and results in lighter colours.

Caractéristiques cliniques

Affected dogs (K^B/K^B or K^B/k^y) develop black coats, as long as they are not also affected by the recessive variant of the E-Locus (e/e). The black colour can be further modified by the effects of the B-Locus and D-Locus.

Additional Information

Coat colour is an intricate trait that involves a combination of multiple different genes. Testing for a range of different loci will give the most complete prediction of a dog's coat colour genetics.

Références

Pubmed ID: 17947548

Omia ID: 1416

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