57,48 47,50 hors TVA

P785

The Dominant White coat colour pattern in horses can be caused by any in a wide array of related mutations.

11 working days

Caractéristiques

Breeds

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Gene

Organ

specimen

Hair, Blood EDTA, Blood Heparin, Semen, Tissue

Mode of Inheritance

Chromosome

Also known as

Year Published

Informations générales

The Dominant White coat colour pattern in horses can be caused by any in a wide array of related mutations. The resulting pattern can vary anywhere between white markings on the face and legs, up to a completely white coat. Depending on both breed and pattern, variants of the Dominant White phenotype may be referred to as Splashed White, White Spotting, Tobiano or Sabino, among others.

The specific variant analysed in this test, known as Sabino 1 (SB1), is caused by a semi-dominant mutation to the gene KIT. It has been observed in the American Quarter Horse, Appaloosa, Haflinger, Lipizzaner and Noriker

Caractéristiques cliniques

The sabino pattern is described as irregular spotting usually on the legs, belly and face, often with roaning around the edges of the white markings. The allele SB1 is semi-dominant; one copy of SB1 allele results in horses with broken Sabino markings and possibly only a small amount of white. Two copies of the SB1 allele result in at least 90% white, also referred to as Sabino-white.

Additional Information

Coat colour is an intricate trait that involves a combination of multiple different genes. Testing for a range of different loci will give the most complete prediction of a horse's coat colour genetics.

Dominant White can be caused by a wide range of mutations. A white-patterned horse that tests as unaffected for a particular mutation will almost certainly be affected by a different one.

Références

Pubmed ID: 16284805

Omia ID: 209

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