€57,48 €47,50 hors TVA
Les taches blanches et blanches dominantes sont contrôlées par le gène KIT.
20 working days
Caractéristiques
Breeds | |
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Gene | |
Organ | |
specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
Mode of Inheritance | |
Chromosome | |
Also known as | |
Year Published |
Informations générales
Les taches blanches et blanches dominantes sont contrôlées par le gène KIT. Le blanc dominant est également décrit comme le locus W et le spotting blanc comme le locus S. Le gène KIT a trois variantes (allèles). L’allèle DW est dominant sur les allèles Ws et N ; L’allèle Ws est dominant sur l’allèle N.
Caractéristiques cliniques
The dominant allele DW results in a white coat colour. One or two copies of the DW allele will result in a white-coated cat with varying degrees of hearing impairment. The allele Ws in white spotting and the allele N has no effect on the coat colour.
Additional Information
The gene/genes controlling the pattern of White Spotting is still unknown. Additionally, not all white spots or patterns result from the KIT-gene as other genes can also have mutations that result in depigmentation phenotypes. Dominant White is distinct from albinism (C-locus) which results from a mutation in the TYR gene that has no known impact on hearing.
Références
Pubmed ID: 25085922
Omia ID: 209