€57,48 €47,50 hors TVA
Multidrug Resistance 1 (MDR1), sometimes known as Ivermectin Sensitivity, is a disorder that affects the blood-brain barrier.
10 working days
Caractéristiques
Breeds | |
---|---|
Gene | |
Organ | |
specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
Mode of Inheritance | |
Chromosome | |
Also known as | |
Year Published |
Informations générales
Multidrug Resistance 1 (MDR1), sometimes known as Ivermectin Sensitivity, is a disorder that affects the blood-brain barrier. As a result, affected animals can be in effect poisoned when given certain drugs as part of standard veterinary procedures. In cats, a variant of the disease is caused by a recessive mutation to the gene ABCB1.
It is estimated that this mutation occurs in approximately 4% of domestic cats.
Caractéristiques cliniques
Affected cats are likely to experience adverse reactions (central nervous system toxicity) to P-glycoprotein substrate drugs such as ivermectin, imidacloprid and selamectin.
Additional Information
Références
Pubmed ID: 25660379
Omia ID: 1402