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Canine Multifocal Retinopathy (CMR) is an eye disorder characterised by multiple areas of retinal degeneration, potentially causing a loss of central vision.
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Caractéristiques
| Breeds | Berger finnois de Laponie, Finnois de Laponie, Lapphund suédois |
|---|---|
| Gene | |
| Chromosome | 18 |
| Mutation | c.1466G>T |
| Mode of Inheritance | Autosomique récessif |
| Organ | |
| Specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Also known as | cmr3; mr3 |
Informations générales
Canine Multifocal Retinopathy (CMR) is an eye disorder characterised by multiple areas of retinal degeneration, potentially causing a loss of central vision. This variant of the disorder, CMR3, occurs specifically in the Lapponian Herder, Swedish Lapphund and the Finnish Lapphund. It is caused by a recessive mutation to the gene BEST1.
Caractéristiques cliniques
On veterinary examination, clinical signs of CMR include multiple tan-pink subretinal patches ("blisters") in both the tapetal and the non-tapetal fundus along with focal areas of tapetal hyper-reflectivity. The disorder does not typically lead to blindness.
Additional Information
Références
Pubmed ID:
Year published:
Omia ID: 1554
Omia variant ID: