POAG / PLL Glaucome Primaire et Luxation de lentille

Primary Open Angle Glaucoma (POAG) is an eye disorder that builds up pressure in the eye and affects the nerves of the retina, causing pain and damaging vision. This variant of the disease, likely caused by a recessive mutation to the gene ADAMTS17, occurs in the Chinese Shar-Pei. The mutation is also associated in this breed with a similar painful eye condition, Primary Lens Luxation (PLL). Similar variants of POAG also occur in the Basset Hound, Petit Basset Griffon Vendéen, and Basset Fauve de Bretagne.