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Primary Lens Luxation (PLL) is an eye condition in which the lens detaches from its normal attachments, leading to displacement (luxation), inflammation, glaucoma, and potential blindness.
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Caractéristiques
| Breeds | Bull Terrier Miniature, Chinois à crête, Patterdale Terrier, Sealyham Terrier, Terrier de chasse allemand, Terrier tibétain, Volpino italien, Jack Russell Terrier, Lancashire Heeler, Parson Russell Terrier, Rat Terrier, Tenterfield Terrier, Toy Fox Terrier, Welsh Terrier, Yorkshire Terrier |
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| Gene | |
| Organ | |
| specimen | Écouvillon, EDTA sanguin, Héparine sanguine, Sperme, Tissu |
| Mode of Inheritance | |
| Chromosome | |
| Also known as | |
| Year Published |
Informations générales
Primary Lens Luxation (PLL) is an eye condition in which the lens detaches from its normal attachments, leading to displacement (luxation), inflammation, glaucoma, and potential blindness. PLL is caused by an autosomal recessive mutation in the ADAM metallopeptidase with thrombospondin type 1 motif 17 (ADAMTS17) gene.
Caractéristiques cliniques
Symptoms of PLL include: redness of the eye, squinting, tearing, a bluish or cloudy haze over the cornea, and visible lens displacement. Early symptoms of PLL can be observed from 20 months of age on. Complete luxation usually appears between 3-8 years of age.
Additional Information
Références
Pubmed ID: 20375329
Omia ID: 588