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A recessive mutation to the keratin gene KRT71 is responsible for the growth of a curly rather than straight coat in certain dogs.
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Caractéristiques
| Breeds | Chien d’eau espagnol, Retriever à poil bouclé, Retriever de la baie de Chesapeake, Terrier irlandais, Bichon Frise, Lagotto Romagnolo |
|---|---|
| Gene | |
| Organ | |
| specimen | Swab, Blood EDTA, Blood Heparin, Semen, Tissue |
| Mode of Inheritance | |
| Chromosome | |
| Year Published |
Informations générales
A recessive mutation to the keratin gene KRT71 is responsible for the growth of a curly rather than straight coat in certain dogs. The variant analysed in this test, designated as c^2, is found in breeds such as the Bichon Frise, Chesapeake Bay Retriever, Curly Coated Retriever and Lagotto Romagnolo. A closely related variant, designated as c^1, is found in the Portuguese Water Dog.
Caractéristiques cliniques
Affected dogs will have curly instead of straight hairs.
Additional Information
Il y a quelques indications que la variante représente probablement un facteur de risque génétique pour certaines formes de dysplasie folliculaire chez le chien.
Références
Pubmed ID: 30444027,30456859
Omia ID: 245
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- Cairn Terrier, Norfolk Terrier
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- Norwegian Lundehund
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- Portuguese Water Dog
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- Basenji
- PKLR
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